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This approach highlights gene therapies versatility in upregulating and downregulating key pathways involved in liver disease progression (Kyritsi et al., 2020)

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The nanoparticles were prepared using an emulsion solvent evaporation method, yielding particles with a mean size of 148.2 4.2 nm, a PDI of 0.12, and a zeta potential of 23.1 3.0 mV, supporting their suitability for BBB penetration

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