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For example, a BMP-2 mimetic peptide known as P20 (KIPKASSVPTELSAISTLYL) was derived from the knuckle antigenic epitope, which represents the core functional region essential for osteogenesis [81]

Substrate specificity of TGM As KCs terminally differentiate into corneocytes, an early step in the formation of the cornified envelope is an attachment of involucrin to the inner surface of the cell membrane in a reaction catalyzed by the essential enzyme, TGM1 (Candi et al., 2005

Depression Depression shows the strongest preclinical foundation

doi:10.1152/jappl.1999.87.6.2274 Nair KS, Rizza RA, O'Brien P, et al