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The pH 8 wash run had higher CVA21 elution yield and was selected as the optimal condition, but further investigation into a pH 7 wash may increase yield and purity

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Comparison of impact of ACore on presynaptic terminal volume and number To investigate the impact of the ACore on the corresponding presynaptic side of the synapse, the volume, surface area, and count per region of interest (ROI) of spine-innervating nerve terminals were assessed in primary hippocampal neuronal cultures using the synaptic vesicle marker, synaptophysin, apposed to PSDs in identified spines (Fig

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