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Description
This paper describes the first structure of a GPCRG-protein complex, highlighting receptor-mediated conformational changes within the G protein that are important for nucleotide release

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Whether SIRT1, SEC, ER and Mediator cooperate in stress responses in ER + BC remains unknown

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Analysis of mitochondrial ultrastructure by transmission electron microscopy Control and NaBt-treated PC12-ND6 cells were fixed in 2.5% glutaraldehyde (Electron Microscopy Sciences), 1% paraformaldehyde in 0.12 M sodium cacodylate buffer (Electron Microscopy Sciences) for 20 min at room temperature followed by 40 min on ice

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