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In the tumor environment, FCS/GCS releases Fe + /Gd + and cinnamaldehyde, which consumes GSH, converting it to GSSG

236 MAT2A has been proposed as a lethal target in MTAP null tumors

Liu, Y., Qin, R., Zaat, S

Given the role of GPx1 in promoting cell survival pathways, the effectiveness of other chemotherapeutic agents, such as the isothiocyanate iberin, may be due, in part, to their ability to decrease GPx1 expression
This disruption may be a critical mechanism underlying fatigue and cognitive impairment in LLD patients
BIBLIOGRAPHY Bilska A., Kryczyk A., Wodek L
