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CCC involves creating a tear in the anterior capsule then continuing the tear in a circular continuous fashion while minimizing shear forces exerted on the zonular fibers

In February 2024, Takeda outlined plans to begin global Phase III trials of TAK-861 in NT1, following Phase IIb results that met all key endpoints and confirmed the therapy was safe and well-tolerated

Improved blood circulation during training helps remove metabolic byproducts, while increased blood circulation at rest facilitates the delivery of nutrients to target muscles, promoting tissue recovery and reducing muscle soreness