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Theres also a possibility that the lipid oxidation was underestimated by the indirect calorimetry, as well, which should be evaluated in more detail in our future study
Psych Clin Neurosci 73(4):187193

Although metformin was initially contraindicated in advanced HF due to the risk of lactic acidosis, recent studies have shown beneficial effects of early administration of metformin in models of HF

2005;1(2):e23

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