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Subsequently many labs showed that a variety of other agents, able to generate an oxidative stress throughH 2 O 2 generation, increasing concentrations of electrophiles or nitric oxide could also induce GCLC or GCLM subunits or both (Rahman et al., 1996

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400 Later-life rapamycin feeding increases lifespan by 14% in females and 9% in males, 401 with a sex difference

Cell 89 , 11111119 (1997)