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This work [170], together with a clinical trial of gene therapy for adrenoleukodystrophy [175], constituted the first trial of the use of a LV for the treatment of an inborn genetic disease to be approved anywhere in the world

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Song WY, Park J, Mendoza-Czatl DG, Suter-Grotemeyer M, Shim D, Hrtensteiner S, et al

It also gives you an early warning system if one pair suddenly feels dramatically different than the other, the softer one's midsole is more mechanically dead than its appearance suggests