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Description
Infection risk Open fissures and excoriated skin create direct entry points for pathogens

It activates multiple overlapping pathways simultaneously, which is part of why its effects appear so broad
Common symptoms include itching, soreness, swelling, discomfort, small amounts of bleeding, and a feeling of fullness or a lump in the back passage

This is one reason why experiences vary so dramatically from person to person

Journal of Biomechanics, 49 , 19261932
It can reduce weight by up to 24% in only 48 weeks, compared to tirzepatide, which reduced weight by 20.9% after 72 weeks
