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New ice rinks generally use ammonia as a refrigerant, but R-22 was the choice for many years, and the ice making systems in older rinks can contain several thousand pounds of R-22

The published research summarized above is provided as scientific reference material

Environmental Science & Technology, 844: 157162 Li D H, Li W G, Zhang D Y, Zhang K L, Lv L Y, Zhang G L (2023)

However, this approach is not routine first-line treatment in UK practice, is considered off-label, and requires good patient adherence and clinical follow-up

The choice of chelating agent and the treatment plan should be tailored to each patients individual needs and medical conditions

Conversely, adequate levels of vitamin B12 and folic acid help synthesize the neurotransmitters necessary for regulating and maintaining emotional well-being