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The transcriptional regulation of the growth hormone gene is conserved in vertebrate evolution

Acquired resistance to BET-PROTACs (proteolysis-targeting chimeras) caused by genomic alterations in core components of E3 ligase complexes

VEGF signaling: VEGF is a mitogenic peptide that is well known for its potent induction of endothelial cell migration, proliferation, and tubule formation ( Supplementary Figure 3B displayed the VEGF-induced sub-epithelial fibrosis via upregulation of TGF- in lung epithelial cells, causing accumulation of collagen I, III, and V, leading to thickening of the basement membrane and subsequent airway remodeling ( Supplementary Figure 3B , which promotes disruption of tight junction barrier integrity in airway epithelium, leading to increased access of inhaled allergens and consequent exacerbation of Th2 inflammatory response ( Supplementary Data

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microglia are more likely to exist along a continuum of functional states, with overlapping features rather than two sharply defined phenotypes

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