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There can also be changes in the skins natural balance of microorganisms

Changes observed in aged mice (12-months-old) include an upregulation of genes associated with the immune response, and a decrease in genes associated with environment probing and interactions with the ECM (Grabert et al., 2016

The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation

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People who are under constant pressure at work or at home, and who feel overwhelming stress as a result, are much more likely to suffer from many diseases [106]

The root cause of this condition lies in the compromised drainage of aqueous humor, a clear fluid produced by the eye to regulate IOP and nourish ocular structures (Praveen et al., 2022)