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It is noteworthy that alcohol-induced alteration of the gut microbiota is one of the major hallmarks of ALD pathogenesis

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For each of the two liquid formulations, bioequivalence with the FD formulation was concluded if the 95% confidence intervals (CIs) for the estimated test/reference ratios of geometric means of AUC 0-t and C max were within the standard pre-specified acceptance range (0.80-1.25)