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Immune disorders are characterized by inflammatory symptoms

Mitochondrial dysfunction induces rapid production of reactive oxygen species (ROS), which is most probably triggered by VPA-directed inception of the mitochondrial permeability transition (MPT) pore, discharge of cytochrome c from mitochondria, and caspase 9 activation, all of which result in mitochondria-directed apoptosis (Zhang et al., 2016)

however, a crucial standard of preclinical efficacy is protection of functional outcomes

Omranifard V, Rajabi F, Mohammadian-Sichani M, Maracy M

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Is increased intracellular calcium in red blood cells a common component in the molecular mechanism causing anemia