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Potentiation of glutathione loss and nerve cell death by the transition metals iron and copper: implications for age-related neurodegenerative diseases

Beau's lines can occasionally signal more severe illnesses like cancer, heart disease, or kidney disease, so it's crucial to keep that in mind as well

doi: 10.1038/s41556-020-0461-8

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Melatonin has been shown to inhibit the expression of key signals involved in initiating apoptosis in rodent models of AD and various brain cell types

Furthermore, evidence points toward exposure between birth and approximately 5 years of age as the period of highest risk, with the risk during prenatal exposure being significant in numerous studies [4] albeit less consequential [2,3]