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Mechanistically, treatment with LR5 combined with skim milk restored the diversity and composition of the gut microbiota increased the abundance of beneficial genera, such as Muribaculaceae and enhanced intestinal barrier integrity by increasing the expression of tight junction proteins, including claudin-1, occludin, and zonula occludens-1

doi: 10.1038/s41556-019-0305-6 [DOI] [PMC free article] [PubMed] [Google Scholar] 46

CrossRef The Differential Expression of Long Noncoding RNAs in Type 2 Diabetes Mellitus and Latent Autoimmune Diabetes in Adults Zhang Pengyu, Yan Yan, Fu Xiying, Yang Maoguang, Li Mo, Cheng Yan, Shen Hong, Wang Lijuan, Zhang Xiujuan, Cai Hanqing International Journal of Endocrinology.2020