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Activation of Nrf2 by natural bioactive compounds: a promising approach for stroke

Some drug metabolites, rather than killing cells, result in mutations through binding to nucleoprotein
Boccia L, Gamakharia S, Coester B, Whiting L, Lutz TA, Le Foll C

doi: 10.1016/j.anireprosci.2021.106686 36 SheikhAAHoodaOKDangAK
Urate as a predictor of the rate of clinical decline in Parkinson's disease

Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression
