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When GPX8 is overexpressed, it leads to a decrease in Ca 2+ levels in the endoplasmic reticulum (Yoboue et al., 2017)

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Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: a comparative crossover study

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It involves the charge transfer process in biochemical reactions where it forms a cofactor and coenzyme, such as tetrahydrobiopterin participate in many enzymatic processes including the synthesis of neurotransmitter 29

Taken together, these results suggest regulation of GS may also be important in determining the overall GSH synthetic capacity under certain conditions and especially in non-hepatic tissues