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Next, we tested if the released TP53 is responsible for the apoptotic signalling cascade by examining known downstream targets of TP53, PMAIP1 (NOXA) and BBC3 (PUMA) [63]

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Nine out of these ten compounds were custom-made by a commercial source, MolPort (www.molport.com) (Figure 2A)

This approach requires the existence and availability of specific ligands for the capture of the fusion protein through an encoded affinity tag tail (Fig

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