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However, iron chelators including deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFX) generally lack tissue and cellular specificity, often resulting in the non-selective depletion of physiologically essential iron

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10.1182/blood.V87.8.3494.bloodjournal8783494 8 AndreaniM.NesciS.LucarelliG.TonucciP.RapaS.AngelucciE.et al

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Dosing is extrapolated from preclinical models [1] [6]

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