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Therefore, cancer cells are often characterized by relatively high ROS levels

Proteotranscriptomics reveal signaling networks in the ovarian cancer microenvironment

During ERS regulation of autophagy gene expression, ATF4 can directly bind to and upregulate multiple autophagy gene promoters to initiate autophagy (Bchir et al., 2013)

Neuroendocrine-immune network The brain is the key organ for regulating fatigue (18), and brain imaging studies have found that the activity and connectivity patterns of brain regions change when patients are fatigued (18,49-51)

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Methods 337 , 715 (2008)