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The kinase PKCalpha selectively upregulates interleukin-17A during Th17 cell immune responses

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This addresses the same pathway as Finasteride, but WITHOUT the 5-alpha reductase inhibition known to cause sexual side effects and neurosteroid depletion

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However, in eukaryotes low levels of ROS and RES act also as second messengers to modulate signal transduction pathways (Rudolph and Freeman, 2009