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Am J Hematol 96(2):241-250, 2021

This coordinates the regulation of key enzymes in lipid metabolism: it inhibits the expression of lipogenic enzymes (FAS and ACC) while upregulating the rate-limiting enzyme for fatty acid -oxidation, CPT1A, thus correcting lipid metabolic imbalance, reducing hepatic lipid deposition, and improving insulin resistance from the metabolic source (72)

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In vivo and in vitro studies suggest that ferroptosis may contribute to DM-related cognitive dysfunction, causing neuronal damage in diabetic animals

[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Yadav S., Dadge S., Garg R., Goand U.K., Agarwal A., Chauhan D., Gayen J.R

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