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Meta-regression analyses for homocysteine, cysteine, and vitamin B12 only showed that publication year was significantly associated with ES, as shown in eFig
doi: 10.1073/pnas.91.21.9745
To further explore the role of the BM microenvironment in promoting mTOR activity in LTR, we analyzed mTOR expression in the non-CAR T cell fraction in the BM, which is composed of non-transduced T cells from the CAR T cell product as well as endogenous reconstituting T cells
In preclinical studies, some nonradioactively labeled ligand-drug complexes constructed by the combination of BN with camptothecin (CPT), doxorubicin (DOX), PTX, and other chemotherapeutic drugs have successfully improved the selectivity and efficacy of these drugs [101]
Amitriptyline pharmacologically preconditions rat hearts against cardiac ischemic-reperfusion injury
However, not all combinations are safe
