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Published studies primarily focus on its interaction with enzymatic and metabolic pathways rather than endocrine signaling systems

Conflict of interest The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

CDI Query Trigger When a patient with Type 2 diabetes is coded only as E11.9 (without complications) and the record shows peripheral neuropathy, numbness, tingling, or burning feet query the physician for confirmation of diabetic neuropathy (E11.40E11.49)

[DOI] [PMC free article] [PubMed] [Google Scholar] 244.Pirinen, E

In fact, NADH is an inhibitor of the TCA enzyme isocitrate dehydrogenase 93 , a protective mechanism to prevent overloading of the ETC and excessive ROS generation