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To view a copy of this licence, visit About this article Cite this article Fan, J., Jiao, J., Chang, HQ

Cummings, R.C

The second step in BH 4 synthesis, catalyzed by 6-pyruvoyltetrahydropterin synthase (PTPS), involves the Zn 2+ and Mg 2+ -dependent rearrangement of 7,8-dihydroneopterin triphosphate, with concommitant loss of the triphosphate, to 6-pyruvoyltetrahydropterin

The correct posture is enthusiasm about the science paired with sobriety about the still-open Phase 3 and safety questions

PMID: 12942553

Hence, the reliable determination of GSH and GSSG in absolute and ratiometric terms in blood and tissues is regarded a putative tool in oxidative stress studies