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The study suggests that LAC deficiency might serve as a biomarker for a specific subtype of MDD, characterized by greater severity and earlier onset

R., Burlina, A

Accordingly, an improved understanding in humans of the microbial pathways involved in TMA/TMAO formation from distinct nutrients is an essential and necessary step in the development of targeted interventions to interrupt these processes

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Additionally, certain pharmacological agents, including cisplatin, downregulate renal OCTN2 expression, increasing urinary carnitine excretion and potential deficiency states (19)

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