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Clinical evidence comes in tiers: mechanistic studies (does the molecule do what it should at the cellular level?), animal studies (does it produce the expected effect in a living organism?), and human trials (does it actually work on the people who will use it?)

After three decades and more than two hundred papers, there is still no published randomized controlled trial showing efficacy

What works in your first trimester might not be what you need in your third

Exposure to heat, moisture, or light accelerates degradation

10.1007/s10616-021-00514-y 202 PangH.ZhouY.WangJ.WuH.LiuX.GaoF.et al (2021)