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Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LB, Lipsky PE

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J Oncol (2021) 2021:6242798

doi: 10.1093/cvr/cvr274

There have been few studies on the mechanism of radiation-induced MPNST, where they found that loss of H3K27me3 expression is a highly sensitive marker for both sporadic and radiation-induced MPNST [25], implying that the post-radiation MPNST may share the same mechanism pathway as sporadic MPNST to some extent