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an experimental study

J Med Food 17(6):663669

The expression of S100A9 in neutrophiles and activated macrophages, cells that produce large amounts of ROS during inflammation, suggests that it protects tissues from oxidative damage (Srikrishna, 2012)

The supernatant was either used for further analysis or complemented with 5x Laemmli buffer containing 10% (v/v) -mercaptoethanol

Thus, during aging, impaired CMA function may induce cellular senescence by degrading HIF-1, which affects p21/CDKn1a

It does this by activating the innate repair receptor (IRR), a heteromer of the EPO receptor and the beta-common receptor (CD131), which simultaneously triggers anti-inflammatory and tissue repair pathways