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Activated microglia release inflammatory factors that impair astrocytic support for neuronal survival, growth, and synaptic homeostasis, worsening neurodegeneration (Alrouji et al., 2019)

Resume retinoid use 48 to 72 hours after microneedling

It acts through monocarboxylate transporters on orexin neurons, and this effect is mediated by ATPsensitive potassium channels composed of Kir6.1 and SUR1 subunits, thus influencing wakefulness and energy homeostasis (Parsons and Hirasawa, 2010)

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Clinics encourage patients to stay briefly for observation, often providing water or light snacks

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