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doi: 10.1124/jpet.112.199497

FIGURE 1 Mammals express four subunits of GIRK channels: GIRK1 (Kir3.1/ KCNJ3 ), GIRK2 (Kir3.2/ KCNJ6 ), GIRK3 (Kir3.3/ KCNJ9 ), and GIRK4 (Kir3.4/ KCNJ5 ) (Luscher and Slesinger, 2010)

Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo

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Large-scale, randomized controlled trials are critically needed to establish definitive efficacy for specific clinical indications and to compare these peptides with established therapies