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This observation suggests that mtDNA-driven cGAS-STING activation may represent a shared pathological feature across these conditions

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it can be a signal that one of them is present

Deamidation of asparagine residues (present in TB-500s Asn in full-length T4, but the fragment contains no asparagine at positions 17-23) accelerates at alkaline pH but is minimized at pH 4-6

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