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These mechanistic sites include neuronal hyperexcitability, A and/or tau protein misfolding/oligomerization, neuroinflammation, reactive oxygen species (ROS) production, and metal dyshomeostasis (Figure 1)
Hydroquinone studies under the National Toxicology Program (NTP)

Furthermore, non-differential misclassification may be an issue, as it is conceivable that control groups in the study could develop cancer in the future

And he had come out of a business meeting
