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The authors suggested that the adduction of Grxs by EdAG suggests the possible alteration of proteins that are normally regulated via Grx-dependent reversible glutathionylation or deglutathionylation

Hum Genet 138:13591377 [DOI] [PMC free article] [PubMed] [Google Scholar] Schiff MH, Jaffe JS, Freundlich B (2014) Head-to-head, randomised, crossover study of oral versus subcutaneous methotrexate in patients with rheumatoid arthritis: drug-exposure limitations of oral methotrexate at doses 15 mg may be overcome with subcutaneous administration

Girault JB, Swanson MR, Meera SS, Grzadzinski RL, Shen MD, Burrows CA, et al