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How common is B6 deficiency

In diabetic state, hyperglycemia leads to overproduction of free radicals (i.e., mitochondrial , NO and peroxynitrite) mainly derived from glucose oxidation and lipid peroxidation, which cause oxidative damage to biomolecules
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It is involved with over 300 cellular metabolic processes

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Effect of glycemic control and vitamin E supplementation on total glutathione content in non-insulin-dependent diabetes mellitus
