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Notably, inactivation of Bach1 is a prerequisite for HO-1 induction, which is dominant over NRF2-mediated HO-1 transcription 53

Immune profiling indicated increased infiltration of cytotoxic T cells, suggesting immunomodulatory benefits ( Genetically Engineered Mouse Models (GEMMs): Although less commonly applied to AgNP studies, GEMMs recapitulate spontaneous tumorigenesis

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We then converted the network to a minimum spanning network to identify alterations in other metabolites that GC analysis did not reveal