in vivo tracing of glutathione Metabolic orchestration driven by GGCT: diverting glutamine to biosynthesis while enhancing glucose anaplerosis for tumor proliferation Frontiers | Glutathione deficiency in

To identify significant differences in gene expression in A2780 and A2780/GSTP1 cells, moderated Student's t -tests were performed using empirical Bayes statistics in the Limma package, and resulting P -values adjusted for multiple testing using the false discovery rate (FDR) Benjamini and Hochberg method (Smyth, 2004)

With anemia of inflammatory disease, the increased iron sequestered within macrophages may actually promote synthesis of ferroportin, which may partly offset the hepcidin- and other cytokine-mediated downregulation or degradation, allowing heme synthesis to continue and preventing a severe anemia in contrast to that seen with a true iron deficiency anemia

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