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Over weeks and months, these repeated temperature cycles accelerate peptide degradation significantly

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Stability, lipidation, and why these peptides last a week The shared design principle behind both molecules is chemical: attach a fatty-diacid side chain (a C18 diacid for semaglutide, a C20 diacid reported for cagrilintide) via a linker so the peptide binds reversibly to circulating albumin