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In rat models, high pulmonary blood flow-induced PH was established through the creation of an abdominal aorta/inferior vena cava shunt

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HIF-3 is a negative regulator of HIF-1, HIF-2 and HIF-3, and HIF-3 has not been studied much (56)

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Mori, Q

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We simply do not yet know whether the second is an effective substitute for the first

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However, this dream has gone largely unfulfilled at the level of clinical medicine because of limitations related to brain delivery and costs

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USA 105 , 1247412479 (2008)

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