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As PPAR induces the expression of genes regulating mitochondrial FAO that were suppressed by oxalate treatment, we next assessed the effects of oxalate on mitochondrial bioenergetics using Seahorse assays

GPX4 depletion alone is not a definitive indicator of ferroptosis, as it is also implicated in alternative cell death pathways, thereby requiring supplementary markers for accurate identification

Neuron 43 , 527537 (2004)

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