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3.4 Lobetyolin's effect on inflammatory markers in the serum and ovaries of DHEA mice Figure 4A shows that the serum levels of TNF-, IL-6, and LPS were markedly increased in the Model group compared to the Control group

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Proline metabolism not only supports collagen synthesis for the extracellular matrix (ECM), but also enables tumor cells to recycle collagen-derived proline under nutrient stress in the tumor microenvironment, promoting tumor growth (84, 85)

doi: 10.1038/sj.onc.1205231
How is this autoregulation mechanism achieved
