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10.1016/j.pain.2013.07.032 73 JanesK.LittleJ

Clean the injection site with alcohol, pinch the skin to create a fold of tissue, insert the needle at a 45-90 degree angle, inject slowly, and withdraw the needle

Methods Enzymol 353:101113

10.1038/nature09486 83 LaubleH.StoutC

While B12 is found naturally in a healthy diet, factors like stress or poor eating habits can lead to a deficiency

These alterations contribute to systemic inflammation by increasing the production of pro-inflammatory cytokines, including interleukin (IL)-1, IL-6, IL-8, IL-13, tumor necrosis factor-alpha (TNF-), and transforming growth factor-beta 1 (TGF-1) [24]
