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Dec 16 2022;14(24)doi:10.3390/nu14245345 Gordon S, Hoey L, McNulty H, et al

Lipid metabolism and ferroptosis Initiation of lipid peroxidation requires the removal of a bis-allylic hydrogen atom (located between two carboncarbon double bonds) from polyunsaturated fatty acyl moieties in phospholipids (PUFA-PLs) incorporated into lipid bilayers

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Indeed, patients with severely compromised GSH levels die early in life, usually before birth (Njalsson and Norgren, 2005

Lancet, 402(10401), 529-544

However, preterm neonates often have deficient Zn levels and subsequent reduced SOD activity