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That lack of energy is known as fatigue, and dealing with it all the time can affect your ability to feel motivated about doing anything, even getting out of bed

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Kaur and Prakash, 2020

doi: 10.1016/j.immuni.2013.08.013, 104 ZhangQ

And proteins maintain their function through their shape

Small molecule protein-protein interaction inhibitors as CNS therapeutic agents: current progress and future hurdles
