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In this context, animal studies have suggested that reactivation of stress-related memories in PTSD models is associated with changes in BDNF expression

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In neurological diseases, functional defects in N-methyl-D-aspartate receptors (NMDARs) are the major defects that cause neural signaling disorders

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The first reaction is a phosphotransferase step that involves an intramolecular attack between the hydroxyl group at the 2' position on the inositol ring and the adjacent phosphate group resulting in a cyclic IP 3 intermediate