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WHAT RESEARCHERS LOOK AT Mechanism: selective small-molecule inhibition of NNMT

One of these regulating mechanisms is the differential tissue expression of prohormone convertase 2 and prohormone convertase 1/3, which allows tissue-specific processing of proglucagon into either glucagon (via prohormone convertase 2) or GLP-1 and glucagon-like peptide 2 via prohormone convertase 1/3 [9] (Fig

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PMID: 25407511 Written by Ali Rza Akn Microbiome Scientist, Author & Founder of Next-Microbiome Ali Rza Akn is a microbiome scientist with nearly 30 years of experience in translational biotechnology, systems biology, and applied microbiome research, spanning discovery, preclinical development, and clinical-stage translation

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