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doi:10.1089/ARS.2009.2695 Morris D, Khurasany M, Nguyen T, et al

In familial early onset PD (EOPD), loss-of-function mutations in PINK1 have been associated with increased levels of glutamatergic transmission in dorsal striatal spiny projection neurons

[29] It has also been linked to optic nerve atrophy and neuritis

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