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Concentrations of 0.1% to 1% are well-supported by trial data

Despite the exact mechanism by which carotenoids inhibit the activity of MAO is not fully elucidated, some studies reported results that emphasize this effect 82

Compounds such as EGCG and apigenin promote apoptosis in melanoma cells by modulating pathways like MAPK and PI3K-AKT, while green tea polyphenols inhibit histone deacetylase (HDAC) and activate histone acetyltransferase (HAT), reactivating tumor-suppressor genes silenced during melanoma progression 138,148

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[DOI] [PubMed] [Google Scholar] Kaya I., Brulls S

Though our focus is on natural therapies, this is a very good time to also add in the antiviral medication Valtrex (Valcyclovir)